Researchers at the University of Birmingham want to hear from people whose depression hasn't responded to antidepressants or talking therapies — sometimes called difficult-to-treat depression.
By understanding this kind of depression better, we hope to help develop new treatments — and to build a research registry that makes it easier to invite people to future trials.
If you're interested in taking part, click below to fill in a short eligibility survey.
If you decide to take part, you'll be asked to:
Take part in a baseline interview phone call, during which you'll give your consent to take part
Attend a first appointment (around 2 hours, online or in person) where the study is explained, and we check your eligibility
Download the DECODE app (developed by Monsenso) and complete a first set of questionnaires about your mental and physical health
Repeat those questionnaires every 3 months for 2 years (longer ones at 12 and 24 months)
You may be eligible to take part if you:
Are aged 16 or over
Have been diagnosed with depression
Have tried at least two antidepressants that didn't relieve your symptoms
Live in the UK and have access to a smartphone
Agree to be contacted about future depression-treatment studies you may be eligible for
Reimbursement is available for your time and travel costs, offered in the form of gift vouchers:
£15 for completing baseline eligibility assessments
£25 for completing baseline questionnaires via the app
£15 for completing all questionnaires every three months
£20 at the year 1 and year 2 time points (due to additional questionnaires)
