Researchers at the University of Birmingham want to hear from people whose depression hasn't responded to antidepressants or talking therapies — sometimes called difficult-to-treat depression.
By understanding this kind of depression better, we hope to help develop new treatments — and to build a research registry that makes it easier to invite people to future trials.
If you're interested in taking part, click below to fill in a short eligibility survey.
If you decide to take part, you'll be asked to:
Take part in a baseline interview phone call, during which you'll give your consent to take part
Attend a first appointment (around 2 hours, online or in person) where the study is explained, and we check your eligibility
Download the DECODE app (developed by Monsenso) and complete a first set of questionnaires about your mental and physical health
Repeat those questionnaires every 3 months for 2 years (longer ones at 12 and 24 months)
Optionally agree to be contacted about future depression-treatment studies you may be eligible for
You may be eligible to take part if you:
Are aged 16 or over
Have been diagnosed with depression
Have tried at least two antidepressants or talking therapy that didn't relieve your symptoms
Live in the UK and have access to a smartphone
Reimbursement is available for your time and travel costs, offered in the form of gift vouchers:
£15 for completing baseline eligibility assessments
£25 for completing baseline questionnaires via the app
£15 for completing all questionnaires every three months
£20 at the year 1 and year 2 time points (due to additional questionnaires)
