Have you had a stroke?
Do you find yourself crying or laughing uncontrollably?

Have you had a stroke?
Do you find yourself crying or laughing uncontrollably?

You may be eligible to take part in a study investigating whether a commonly used medicine can help people who experience emotionalism after stroke, the sudden, uncontrollable urge to cry or laugh that affects 1 in 5 stroke survivors.


If you're interested in taking part, click below to find out more and register your interest.

Who can take part?

Who can take part?

You may be eligible to take part if you:

Are over the age of 18

Have had a stroke

Experience episodes of crying or laughing that feel sudden or difficult to control

Are based in the UK

Interested in taking part? Click below to find out more and register your interest.

About the study

You'll be randomly assigned to receive either the study medication or a placebo for 6 months, with an equal chance of receiving either. Neither you nor the research team will know which you receive.

This study has been designed to be completed from home, but some people may need to attend clinic visits for safety assessments.

What's involved

In addition to taking your assigned medication, you'll complete short questionnaires at the start of the study, and again at 3, 6, and 12 months after joining. These can be done by phone, video call, online, or on paper, whichever works best for you. The team will also check in with you regularly during the trial.

Take part in our research

Take part in our research

Emotionalism after stroke is common but poorly understood, and current treatment options are limited. Your participation could help shape NHS care for future stroke survivors.


If you're interested in taking part, click below to find out more and register your interest.

Emotionalism after stroke is common but poorly understood, and current treatment options are limited. Your participation could help shape NHS care for future stroke survivors.


If you're interested in taking part, click below to find out more and register your interest.

The EASE trial has been reviewed and approved by the North East – Tyne & Wear South Research Ethics Committee (IRAS number: 1008638).

The EASE trial has been reviewed and approved by the North East – Tyne & Wear South Research Ethics Committee (IRAS number: 1008638).

All rights reserved. Copyright 2026.

All rights reserved. Copyright 2026.