New clinical trial for MA withdrawal support

Researchers are conducting a trial to test a known medication as a treatment for MA withdrawal symptoms.

If you're interested in taking part in this study, click below to fill in an expression of interest form, and a member of the study team will get in touch with you.

MA is now the most common illicit drug for which people seek treatment in Australia, and poorly managed MA withdrawal is a major obstacle to achieving their treatment goals.

About the study

About the study

About the study

The medication being tested in this trial is a known and approved medication and has been used successfully to treat MA withdrawal in the past. This trial is comparing its effectiveness with a placebo when given alongside the usual standard of care.

The medication being tested in this trial is a known and approved medication and has been used successfully to treat MA withdrawal in the past. This trial is comparing its effectiveness with a placebo when given alongside the usual standard of care.

The medication being tested in this trial is a known and approved medication and has been used successfully to treat MA withdrawal in the past. This trial is comparing its effectiveness with a placebo when given alongside the usual standard of care.

Who can take part?

You may be eligible to take part* if you are:

  • 18 or older

  • Currently using MA

  • Seeking MA withdrawal treatment

  • Willing and able to provide informed consent to take part in the trial

*Additional eligibility criteria apply

Who can take part?

You may be eligible to take part* if you are:

  • 18 or older

  • Currently using MA

  • Seeking MA withdrawal treatment

  • Willing and able to provide informed consent to take part in the trial

*Additional eligibility criteria apply

Who can take part?

You may be eligible to take part* if you are:

  • 18 or older

  • Currently using MA

  • Seeking MA withdrawal treatment

  • Willing and able to provide informed consent to take part in the trial

*Additional eligibility criteria apply

Who can take part?

You may be eligible to take part* if you are:

  • 18 or older

  • Currently using MA

  • Seeking MA withdrawal treatment

  • Willing and able to provide informed consent to take part in the trial

*Additional eligibility criteria apply

Who can take part?

You may be eligible to take part* if you are:

  • 18 or older

  • Currently using MA

  • Seeking MA withdrawal treatment

  • Willing and able to provide informed consent to take part in the trial

*Additional eligibility criteria apply

What's involved

You'll be asked to come in to a hospital withdrawal management unit for a 7 day inpatient stay.

You'll be given either the medication we are testing or a placebo in incrementally smaller doses over the 7 days.


You'll also have access to the usual standard of care for withdrawal treatment (including psychosocial support) to help manage your symptoms.

After the 7 days, ongoing support will be provided for both groups.

What's involved

You'll be asked to come in to a hospital withdrawal management unit for a 7 day inpatient stay.

You'll be given either the medication we are testing or a placebo in incrementally smaller doses over the 7 days.


You'll also have access to the usual standard of care for withdrawal treatment (including psychosocial support) to help manage your symptoms.

After the 7 days, ongoing support will be provided for both groups.

What's involved

You'll be asked to come in to a hospital withdrawal management unit for a 7 day inpatient stay.

You'll be given either the medication we are testing or a placebo in incrementally smaller doses over the 7 days.


You'll also have access to the usual standard of care for withdrawal treatment (including psychosocial support) to help manage your symptoms.

After the 7 days, ongoing support will be provided for both groups.

What's involved

You'll be asked to come in to a hospital withdrawal management unit for a 7 day inpatient stay.

You'll be given either the medication we are testing or a placebo in incrementally smaller doses over the 7 days.


You'll also have access to the usual standard of care for withdrawal treatment (including psychosocial support) to help manage your symptoms.

After the 7 days, ongoing support will be provided for both groups.

What's involved

You'll be asked to come in to a hospital withdrawal management unit for a 7 day inpatient stay.

You'll be given either the medication we are testing or a placebo in incrementally smaller doses over the 7 days.


You'll also have access to the usual standard of care for withdrawal treatment (including psychosocial support) to help manage your symptoms.

After the 7 days, ongoing support will be provided for both groups.

Take part in this study

Take part in this study

Take part in this study

If you're interested in taking part please click below to fill in an expression of interest form, and a member of the study team will get in touch with you.

If you're interested in taking part please click below to fill in an expression of interest form, and a member of the study team will get in touch with you.

The ethical aspects of this research project have been approved by the HREC of St Vincent’s Hospital Sydney, Ethics Application reference 2024/ETH00788 and The Aboriginal Health and Medical Research Council of NSW HREC, Ethics reference 2312/24.

All rights reserved. Copyright 2026.

All rights reserved. Copyright 2026.