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Thinking of stopping your antidepressant?

Thinking of stopping your antidepressant?

The PRADAM study is looking for people who are feeling well and thinking about stopping antidepressants. Join this important research.

Who can take part?

Who can take part?

We are looking for volunteers who would like to help us understand what happens when antidepressant medications are stopped. You may be eligible to take part if you:

Are between 18 and 64 years old

Have recovered from depression

Are still regularly taking antidepressant medication

Are willing to come to UCL for two whole days

Have no unremovable magnetic parts in your head

Interested in taking part? Click below to register your interest.

What's involved?

Registration & screening

Fill in a short online form and some questionnaires. We'll check if you're eligible and get in touch.

Online Computer Tasks

Complete simple game-like computer tasks and questionnaires at home. These help us understand how you learn and how you're feeling.

Come to UCL for two whole-day study visits

On each of the visits, you will have brain scans and be given a specific diet for the day.

Stop your antidepressants

You will gradually reduce and then stop your antidepressant medication.

Follow-up

Over 6 months, stay in touch with the dedicated research team to monitor for depression relapses.

Time commitment

2 whole days plus 3 hours over the course of 6 months

Compensation

You will be compensated for your time, receiving up to £250.

Take part in our research

Take part in our research

If you are interested, please click below to complete a short expression of interest form. A member of the study team will contact you to provide more information and determine eligibility.

If you are interested, please click below to complete a short expression of interest form. A member of the study team will contact you to provide more information and determine eligibility.

This study has been reviewed and given a favourable opinion by a research ethics committee.

This study has been reviewed and given a favourable opinion by a research ethics committee.

All rights reserved. Copyright 2026.

All rights reserved. Copyright 2026.